Modern Approaches To Cardiovascular Amyloidosis Treatment

Cardiovascular (cardiac) amyloidosis (CA) is a clinical pathology, usually of geneticallymediated nature, initiated by the precipitation process insoluble fibrous protein with β-pleated sheet secondary structure. Such anomalous changes lead to formation amyloid fibrils, which may give rise various forms amyloidosis. Amyloid can be found in organs and systems, such as cardiovascular system, central peripheral nervous liver, urinary tract, etc. CA rare degenerative disease resulting congestive cardiac failure heart arrhythmia subsequent untimely death. Unfortunately, up date, choice medications for treating very limited. In this paper, we review clinically used pharmaceutical drugs treatment, along some delivery systems compounds.